What is a “Modified Nucleotide” according to MPEP 2412.03(e)?

According to MPEP 2412.03(e), a “Modified nucleotide” is defined as follows:

“Modified nucleotide” includes any nucleotide as described in paragraph 3(f) of WIPO Standard ST.26.

Further explanation from WIPO Standard ST.26 states that a modified nucleotide is any nucleotide other than the standard DNA and RNA nucleotides. Specifically, it excludes:

• deoxyadenosine 3′-monophosphate
• deoxyguanosine 3′-monophosphate
• deoxycytidine 3′-monophosphate
• deoxythymidine 3′-monophosphate
• adenosine 3′-monophosphate
• guanosine 3′-monophosphate
• cytidine 3′-monophosphate
• uridine 3′-monophosphate

To learn more:

• Modified Nucleotide
• WIPO Standard ST.26
• Nucleotide Sequence
• Patent Application
• Biotechnology