How does WIPO Standard ST.26 relate to the definition of “Modified Nucleotide” in MPEP 2412.03(e)?

MPEP 2412.03(e) directly references WIPO Standard ST.26 for the definition of “Modified Nucleotide”: “Modified nucleotide” includes any nucleotide as described in paragraph 3(f) of WIPO Standard ST.26. The MPEP further elaborates on WIPO Standard ST.26’s definition: “WIPO Standard ST.26, paragraph 3(f), identifies that a “modified nucleotide” means any “nucleotide” as explained in MPEP § 2412.03(d)…

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What are the standard nucleotides not considered as “Modified Nucleotides” according to MPEP 2412.03(e)?

MPEP 2412.03(e) provides a list of standard nucleotides that are not considered “Modified Nucleotides”. These are: deoxyadenosine 3′-monophosphate deoxyguanosine 3′-monophosphate deoxycytidine 3′-monophosphate deoxythymidine 3′-monophosphate adenosine 3′-monophosphate guanosine 3′-monophosphate cytidine 3′-monophosphate uridine 3′-monophosphate These nucleotides represent the standard DNA (first four) and RNA (last four) building blocks. Any nucleotide that is not one of these standard…

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What is a “Modified Nucleotide” according to MPEP 2412.03(e)?

According to MPEP 2412.03(e), a “Modified nucleotide” is defined as follows: “Modified nucleotide” includes any nucleotide as described in paragraph 3(f) of WIPO Standard ST.26. Further explanation from WIPO Standard ST.26 states that a modified nucleotide is any nucleotide other than the standard DNA and RNA nucleotides. Specifically, it excludes: deoxyadenosine 3′-monophosphate deoxyguanosine 3′-monophosphate deoxycytidine…

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How does the definition of “Modified Nucleotide” in MPEP 2412.03(e) affect patent applications?

The definition of “Modified Nucleotide” in MPEP 2412.03(e) affects patent applications in several ways: Application Date: It applies to applications filed on or after July 1, 2022. Sequence Disclosure: It’s relevant for applications with nucleotide and/or amino acid sequence disclosures. Sequence Listing: Modified nucleotides must be properly identified and described in the sequence listing of…

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