What are the reasons for withdrawing a patent application from issue?

There are several reasons why an applicant or the USPTO might withdraw a patent application from issue:

• Discovery of new prior art: If relevant prior art is found that could affect patentability
• Errors in the application: To correct mistakes or omissions in the application
• Desire to file a Request for Continued Examination (RCE): To introduce new amendments or evidence
• Interference proceedings: If an interference is declared involving the application
• National security concerns: For applications that may impact national security

According to MPEP 1308: “A petition under 37 CFR 1.313(c) to have an application withdrawn from issue should be filed if applicant desires to have an information disclosure statement considered or to have prosecution reopened.”