How should regions of consecutive modified nucleotides be described in a patent application?

According to MPEP 2412.05(b), regions of consecutive modified nucleotides in patent applications should be described as follows:

• Describe the region in a feature table as required for a modified nucleotide
• Modified nucleotides in the region can be jointly described in a single INSDFeature element
• Provide the most restrictive unabbreviated chemical name or a list of chemical names in the “note” qualifier
• If an individual modified nucleotide in the region has an additional modification, describe it separately in the feature table

The MPEP states, “A nucleotide sequence including one or more regions of consecutive modified nucleotides that share the same backbone moiety must be further described in a feature table as required for a modified nucleotide.” This approach ensures comprehensive and accurate description of modified nucleotide regions in patent applications.

To learn more:

• modified nucleotides
• consecutive regions
• feature table
• WIPO Standard ST.26