How are codons that span introns represented in sequence listings?

The MPEP addresses the representation of codons that span introns in 37 CFR 1.822(c)(3). Specifically, it states:

“In those situations, the ‘amino acid symbol shall be listed below the portion of the codon containing two nucleotides.'”

This requirement clarifies how to represent an amino acid corresponding to a codon that spans an intron. It ensures that the amino acid is aligned with the majority of its corresponding codon, providing a clear and consistent representation in the sequence listing.

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Topics: MPEP 2400 - Biotechnology, MPEP 2423.02 - Depiction Of Coding Regions, Patent Law, Patent Procedure
Tags: biotechnology patents, Codons, Introns, nucleotide sequences, Sequence Listings