What are the key differences between WIPO ST.25 and WIPO ST.26 for sequence listings?

This page is an FAQ based on guidance from the Manual of Patent Examining Procedure. It is provided as guidance, with links to the ground truth sources. This is information only: it is not legal advice.

While MPEP § 2431 doesn’t directly compare WIPO ST.25 and ST.26, it indicates a significant change in requirements:

“See MPEP §§ 2412 – 2419 for guidance on WIPO ST.26 requirements for applications filed on or after July 1, 2022.”

Key differences include:

• Format: ST.26 uses XML format, while ST.25 used a text-based format
• Scope: ST.26 covers more types of sequences
• Mandatory inclusion: ST.26 has different rules for which sequences must be included
• Annotation: ST.26 allows for more detailed sequence annotations

Applicants should refer to the specific MPEP sections for detailed guidance on the new requirements.