How should applicants establish a nexus between an intermediate and an end product’s unexpected properties?

When claiming patentability of an intermediate based on an end product’s properties, MPEP 716.02(b) provides specific guidance: “In order to establish that the claimed intermediate is a ‘contributing cause’ of the unexpectedly superior activity or property of an end product, an applicant must identify the cause of the unexpectedly superior activity or property (compared to…

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