How should modified and unusual amino acids be represented in a sequence listing?
The MPEP 2423.01 provides specific guidance on representing modified and unusual amino acids in a sequence listing: “Modified and unusual amino acids must be represented as the corresponding unmodified amino acids in the sequence itself but may be further described in the feature section of the sequence listing.” This means that: In the main sequence,…
Read MoreHow should modified bases or amino acids be represented in a Sequence Listing?
According to MPEP 2423.01, modified bases or amino acids should be represented in a Sequence Listing as follows: If the modified base or amino acid is listed in Appendices B and D to Subpart G of Part 1 of the CFR, it can be presented as the corresponding unmodified base or amino acid in the…
Read MoreWhat are the rules for representing modified amino acids in WIPO ST.25 sequence listings?
What are the rules for representing modified amino acids in WIPO ST.25 sequence listings? The representation of modified amino acids in WIPO ST.25 sequence listings follows specific rules as outlined in MPEP 2423: “Modified amino acids must be represented as the corresponding unmodified amino acids in the sequence itself if possible. Any modified amino acids…
Read MoreHow are modified amino acids represented in sequence listings?
Modified amino acids in sequence listings are represented according to specific guidelines outlined in MPEP 2412.05(d): Modified amino acids should be represented as the corresponding unmodified amino acid in the sequence itself whenever possible. The modified amino acid must be further described in the Feature section of the sequence listing. As stated in the MPEP,…
Read MoreHow are modified amino acids represented in a sequence listing?
According to MPEP 2412.05(d), modified amino acids should be represented as follows: Represent as the corresponding unmodified amino acid when possible Use ‘X’ for modified amino acids that cannot be represented by other symbols Provide further description in a feature table The MPEP states, “WIPO Standard ST.26, paragraph 29, specifies that modified amino acids, including…
Read MoreWhat is considered an “amino acid” in a Sequence Listing XML?
According to MPEP 2412.03(b), an “amino acid” in a Sequence Listing XML includes: Any D- or L-amino acid Modified amino acids as defined in WIPO Standard ST.26 Amino acids with modified or synthetic side chains The MPEP states: Amino acids will be construed as unmodified L-amino acids unless further described in a feature table. It’s…
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