How should naturally occurring mutations be represented in nucleic acid sequences?

According to the table in MPEP 2412.05(c), naturally occurring mutations in nucleic acid sequences should be represented as follows:

  • Feature Key: variation
  • Qualifier: replace or note
  • Use: For naturally occurring mutations and polymorphisms, such as alleles and RFLPs (Restriction Fragment Length Polymorphisms)

This representation allows for proper documentation of genetic variations in patent applications related to biotechnology.

To learn more:

Topics: MPEP 2400 - Biotechnology, MPEP 2412.05(C) - Representation And Inclusion Of Variants, Patent Law, Patent Procedure
Tags: biotechnology patents, Mutations, Nucleic Acid Sequences, Polymorphisms, sequence listing