MPEP 2412.03(e) provides a list of standard nucleotides that are not considered “Modified Nucleotides”. These are: deoxyadenosine 3′-monophosphate deoxyguanosine 3′-monophosphate deoxycytidine 3′-monophosphate deoxythymidine 3′-monophosphate adenosine 3′-monophosphate guanosine 3′-monophosphate cytidine 3′-monophosphate uridine 3′-monophosphate These nucleotides represent the standard DNA (first four) and RNA (last four) building blocks. Any nucleotide that is not one of these standard…

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