Are there additional fees for submitting large Sequence Listing files?
Yes, there are additional fees for submitting large Sequence Listing files to the USPTO. The fee structure is as follows: Sequence Listing ASCII plain text files of 300 MB or more are subject to a fee under 37 CFR 1.21(o). The fee is divided into two tiers: Tier 1: File sizes 300 MB to 800…
Read MoreHow does the USPTO determine if a Sequence Listing XML is “non-lengthy”?
The USPTO determines if a Sequence Listing XML is “non-lengthy” based on the size of the ASCII text file produced after transforming the XML file. According to MPEP 2419.01: “Upon transformation of the .xml file using the style sheet to an ASCII text file, any ASCII text file produced by the USPTO that is under…
Read MoreWhat are the size restrictions for ASCII plain text files submitted via the USPTO patent electronic filing system?
The USPTO has specific size restrictions for ASCII plain text files submitted via their patent electronic filing system: The size limit for “Sequence Listing” ASCII plain text files is 100 megabytes. Compression is not allowed for “Sequence Listing” files submitted via the USPTO patent electronic filing system. For “Large Tables” and “Computer Program Listing Appendix”…
Read MoreHow should the <213> numeric identifier be used in a sequence listing?
The numeric identifier in a sequence listing has a specific use according to the Manual of Patent Examining Procedure (MPEP). As stated in MPEP 2424.02: “ is used for the name of the organism from which the sequence was obtained” This means that when providing a sequence listing, you should use the identifier to specify…
Read MoreHow should unknown amino acids be represented in a sequence listing?
The MPEP 2412.05(d) provides guidance on representing unknown amino acids in sequence listings: Use the symbol ‘X’ to represent unknown amino acids Provide further description in a feature table Use the feature key “UNSURE” and optionally the qualifier “note” The MPEP states, “Any “unknown” amino acid must be represented by the symbol “X” in the…
Read MoreHow should unbranched nucleotide sequences be presented in patent applications?
How should unbranched nucleotide sequences be presented in patent applications? According to MPEP 2421.02, unbranched nucleotide sequences in patent applications must be presented as follows: They must be listed using a single letter code for nucleotide bases. Sequences with 10 or more nucleotides must be represented in the sequence listing. Each sequence must be assigned…
Read MoreWhat statement must be included in the transmittal letter for sequence listing submissions on compact disc?
When submitting a sequence listing on compact disc, a specific statement must be included in the transmittal letter. According to MPEP 2422.03: “A statement that the content of the compact disc is duplicative of the written sequence listing, if such a written sequence listing is filed with the application, must be included in the transmittal…
Read MoreHow can I submit a Computer Readable Form (CRF) of a Sequence Listing?
According to MPEP 2421.01, there are two main ways to submit a Computer Readable Form (CRF) of a Sequence Listing: On a read-only optical disc As an ASCII plain text file via the Office patent electronic filing system The MPEP states: The CRF may be submitted on read-only optical disc or may be submitted as…
Read MoreHow does the ST.26 Standard affect Sequence Listing submissions?
How does the ST.26 Standard affect Sequence Listing submissions? The ST.26 Standard, as mentioned in MPEP 2415.01, has significantly impacted Sequence Listing submissions: It requires all Sequence Listings to be in XML format It applies to applications filed on or after July 1, 2022 It affects both national and international applications The MPEP states: “For…
Read MoreWhat is the difference between ST.25 and ST.26 for Sequence Listings?
What is the difference between ST.25 and ST.26 for Sequence Listings? The main differences between ST.25 and ST.26 for Sequence Listings, as implied in MPEP 2415.01, are: Format: ST.25 used a text-based format, while ST.26 requires XML format Application Date: ST.25 applied to applications filed before July 1, 2022, while ST.26 applies to applications filed…
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