What is considered a “specifically defined” nucleotide or amino acid?
According to MPEP 2412.03(a), “specifically defined” refers to: For nucleotides: any nucleotide other than those represented by the symbol “n” For amino acids: any amino acid other than those represented by the symbol “X” The MPEP cites WIPO Standard ST.26, which provides tables of symbols for nucleotides and amino acids. For example, ‘a’ represents adenine,…
Read MoreWhat is considered a “nucleotide” in a Sequence Listing XML?
According to MPEP 2412.03(d), a “nucleotide” in a Sequence Listing XML includes: Any nucleotide Nucleotide analogs Modified nucleotides The MPEP, citing WIPO Standard ST.26, specifies that a nucleotide must contain: A backbone moiety (e.g., 2′ deoxyribose 5′ monophosphate or an analogue) Either a nucleobase (including modified or synthetic purines or pyrimidines) or an “AP site”…
Read MoreWhat symbols should be used for representing nucleotides in a sequence listing?
The MPEP 2423.01 specifies the symbols to be used for representing nucleotides in a sequence listing: “The bases in nucleotide sequences must be represented using the one-letter code for nucleotide sequence characters. Only lower case letters in conformity with the list given in WIPO Standard ST.25 (1998), Appendix 2, Table 1, may be used.” The…
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