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How does the MPEP define “AP sites” or “abasic sites” in nucleotide sequences?

By russ.krajec@blueironip.com | September 29, 2024

The MPEP 2412.03(d) addresses “AP sites” or “abasic sites” in the context of nucleotide sequences. According to the MPEP: “[A nucleotide can be] lacking a purine or pyrimidine nucleobase when the nucleotide is part of a nucleotide sequence, referred to as an ‘AP site’ or an ‘abasic site’.” In other words, an AP site or…

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