How should amino acid sequence variants produced by alternative splicing be represented?
According to the table in MPEP 2412.05(c), amino acid sequence variants produced by alternative splicing should be represented as follows: Feature Key: VAR_SEQ Qualifier: note Use: For variants produced by alternative splicing, alternative promoter usage, alternative initiation, and ribosomal frameshifting This representation allows for accurate documentation of protein variants resulting from different cellular processes, which…
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