How should circular nucleotide sequences be represented in patent applications?

According to MPEP 2412.05(b), circular nucleotide sequences in patent applications should be represented as follows: The applicant must choose the nucleotide in residue position number 1 Numbering is continuous throughout the entire sequence in the 5′ to 3′ direction The last residue position number must equal the total number of nucleotides in the sequence The…

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