When does a biological material deposit need to be made?

According to MPEP 2411.02, a biological material deposit must be made on or before the date of payment of the issue fee, unless it has been made earlier in the application process. The MPEP states: “…applicant may reply, pursuant to 37 CFR 1.809(b)(1), by either making an acceptable original, replacement, or supplemental deposit in accordance…

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