MPEP § 2413.01(i) — Title Element in “Sequence Listing XML” (Annotated Rules)

§2413.01(i) Title Element in “Sequence Listing XML”

USPTO MPEP version: BlueIron's Update: 2025-12-31

This page consolidates and annotates all enforceable requirements under MPEP § 2413.01(i), including statutory authority, regulatory rules, examiner guidance, and practice notes. It is provided as guidance, with links to the ground truth sources. This is information only, it is not legal advice.

Title Element in “Sequence Listing XML”

This section addresses Title Element in “Sequence Listing XML”. Primary authority: 37 CFR 1.831(b). Contains: 1 requirement, 1 permission, and 3 other statements.

Key Rules

Topic

Article 19 Amendment Scope

2 rules
StatutoryInformativeAlways
[mpep-2413-01-i-e2fb98cfef047b3581a05bfd]
Invention Title Must Be In English for USPTO
Note:
The InventionTitle element in the general information part of the Sequence Listing XML must be provided in English when filed with the USPTO.

The element InventionTitle described in the table of elements of the general information part (reproduced in MPEP § 2413.01(f) from WIPO Standard ST.26, paragraph 45) as a required element of the “general information” part of the “Sequence Listing XML” must be in the language of filing. It is possible for an applicant to provide more than one InventionTitle element of the general information part in more than one language. However, when the USPTO is the Receiving Office (RO/US) for an international application, the English language is required for the InventionTitle element and also for language-dependent free text of the “Sequence Listing XML.” (See MPEP § 2413.01(h) for more information about language-dependent free text.) If non-English language is presented to RO/US for a “Sequence Listing XML,” then RO/US will transfer the international application to the International Bureau, under PCT Rule 19.4.

Jump to MPEP SourceArticle 19 Amendment ScopeReceiving Office (RO/US)PCT Article 19 Amendments
StatutoryInformativeAlways
[mpep-2413-01-i-bdf309bca2d907db56fb94ae]
Non-English Sequence Listing XML Requires International Transfer
Note:
If a non-English language is used in the 'Sequence Listing XML', the application will be transferred to the International Bureau under PCT Rule 19.4.

The element InventionTitle described in the table of elements of the general information part (reproduced in MPEP § 2413.01(f) from WIPO Standard ST.26, paragraph 45) as a required element of the “general information” part of the “Sequence Listing XML” must be in the language of filing. It is possible for an applicant to provide more than one InventionTitle element of the general information part in more than one language. However, when the USPTO is the Receiving Office (RO/US) for an international application, the English language is required for the InventionTitle element and also for language-dependent free text of the “Sequence Listing XML.” (See MPEP § 2413.01(h) for more information about language-dependent free text.) If non-English language is presented to RO/US for a “Sequence Listing XML,” then RO/US will transfer the international application to the International Bureau, under PCT Rule 19.4.

Jump to MPEP SourceArticle 19 Amendment ScopeReceiving Office (RO/US)PCT Article 19 Amendments
Topic

Sequence Listing Content

1 rules
StatutoryInformativeAlways
[mpep-2413-01-i-3ccdd2fc90abb868e1dd1832]
XML Format for Sequence Listings Required
Note:
This rule requires that all applications with a filing date on or after July 1, 2022, and containing nucleotide or amino acid sequences must use the specified XML format for their sequence listings.

[Editor Note: This section is applicable to all applications with a filing date, or, for national phase applications, an international filing date, on or after July 1, 2022, having disclosure of one or more nucleotide and/or amino acid sequences as defined in 37 CFR 1.831(b). Formatting representations of XML (eXtensible Markup Language) elements in this section appear different than shown in Standard ST.26, which may be accessed at: www.wipo.int /export/sites/www/standards/en/pdf/03-26-01.pdf.]

Jump to MPEP Source · 37 CFR 1.831(b)Sequence Listing ContentSequence Listing RequirementsSequence Listing Format
Topic

Sequence Listing Format

1 rules
StatutoryPermittedAlways
[mpep-2413-01-i-79b837d895196f6aa523afe5]
XML Elements Must Conform to Standard ST.26
Note:
The rule requires that the formatting of XML elements in sequence listings must conform to the standards defined in WIPO Standard ST.26.

[Editor Note: This section is applicable to all applications with a filing date, or, for national phase applications, an international filing date, on or after July 1, 2022, having disclosure of one or more nucleotide and/or amino acid sequences as defined in 37 CFR 1.831(b). Formatting representations of XML (eXtensible Markup Language) elements in this section appear different than shown in Standard ST.26, which may be accessed at: www.wipo.int /export/sites/www/standards/en/pdf/03-26-01.pdf.]

Jump to MPEP Source · 37 CFR 1.831(b)Sequence Listing FormatSequence Listing RequirementsSequence Listing Content
Topic

Receiving Office (RO/US)

1 rules
StatutoryRequiredAlways
[mpep-2413-01-i-8ad7b05b0366522f3e4f7e81]
Invention Title Must Be In English for USPTO
Note:
When the USPTO is the Receiving Office for an international application, the InventionTitle element and all language-dependent free text in the Sequence Listing XML must be in English.

The element InventionTitle described in the table of elements of the general information part (reproduced in MPEP § 2413.01(f) from WIPO Standard ST.26, paragraph 45) as a required element of the “general information” part of the “Sequence Listing XML” must be in the language of filing. It is possible for an applicant to provide more than one InventionTitle element of the general information part in more than one language. However, when the USPTO is the Receiving Office (RO/US) for an international application, the English language is required for the InventionTitle element and also for language-dependent free text of the “Sequence Listing XML.” (See MPEP § 2413.01(h) for more information about language-dependent free text.) If non-English language is presented to RO/US for a “Sequence Listing XML,” then RO/US will transfer the international application to the International Bureau, under PCT Rule 19.4.

Jump to MPEP SourceReceiving Office (RO/US)PCT International Application FilingSequence Listing Format

Citations

Primary topicCitation
Sequence Listing Content
Sequence Listing Format
37 CFR § 1.831(b)
Article 19 Amendment Scope
Receiving Office (RO/US)
MPEP § 2413.01(f)
Article 19 Amendment Scope
Receiving Office (RO/US)
MPEP § 2413.01(h)
Article 19 Amendment Scope
Receiving Office (RO/US)
PCT Rule 19.4

Source Text from USPTO’s MPEP

This is an exact copy of the MPEP from the USPTO. It is here for your reference to see the section in context.

BlueIron Last Updated: 2025-12-31