MPEP § 2413.01(b) — The “Sequence Listing XML” Must Be Valid According To the DTD (Annotated Rules)

§2413.01(b) The “Sequence Listing XML” Must Be Valid According To the DTD

USPTO MPEP version: BlueIron's Update: 2025-12-31

This page consolidates and annotates all enforceable requirements under MPEP § 2413.01(b), including statutory authority, regulatory rules, examiner guidance, and practice notes. It is provided as guidance, with links to the ground truth sources. This is information only, it is not legal advice.

The “Sequence Listing XML” Must Be Valid According To the DTD

This section addresses The “Sequence Listing XML” Must Be Valid According To the DTD. Primary authority: 37 CFR 1.833 and 37 CFR 1.833(b)(1). Contains: 2 requirements and 1 other statement.

Key Rules

Topic

Sequence Listing Format

3 rules
StatutoryRequiredAlways
[mpep-2413-01-b-6ad126faf8602e54239fa351]
Sequence Listing XML Must Be Valid According to DTD
Note:
The 'Sequence Listing XML' must conform to the Document Type Definition as specified in WIPO Standard ST.26, Annex II.
(b) The “Sequence Listing XML” presented in accordance with paragraph (a) of this section must further:
  • (1) Be valid according to the Document Type Definition (DTD) as presented in WIPO Standard ST.26, Annex II.
Jump to MPEP Source · 37 CFR 1.833Sequence Listing FormatSequence Listing RequirementsSequence Listing Content
StatutoryRequiredAlways
[mpep-2413-01-b-c7d6a65632318ac924addee4]
Sequence Listing XML Must Conform to DTD
Note:
A 'Sequence Listing XML' must adhere to the Document Type Definition specified in Annex II of WIPO Standard ST.26.

37 CFR 1.833(b)(1) incorporates the DTD requirement of WIPO Standard ST.26 such that a “Sequence Listing XML” must conform to the Document Type Definition (the document that sets out the structure and use of elements and attributes in an XML compliant document) presented in Annex II of WIPO Standard ST.26. Use of the WIPO Sequence tool will enable a user to generate a “Sequence Listing XML” that conforms to the DTD in Annex II of WIPO Standard ST.26. See MPEP § 2418.

Jump to MPEP Source · 37 CFR 1.833(b)(1)Sequence Listing FormatSequence Listing RequirementsSequence Listing Content
StatutoryInformativeAlways
[mpep-2413-01-b-5c602c265120ce7b7c5122e0]
Requirement for Sequence Listing XML Conforming to DTD
Note:
The 'Sequence Listing XML' must conform to the Document Type Definition specified in Annex II of WIPO Standard ST.26.

37 CFR 1.833(b)(1) incorporates the DTD requirement of WIPO Standard ST.26 such that a “Sequence Listing XML” must conform to the Document Type Definition (the document that sets out the structure and use of elements and attributes in an XML compliant document) presented in Annex II of WIPO Standard ST.26. Use of the WIPO Sequence tool will enable a user to generate a “Sequence Listing XML” that conforms to the DTD in Annex II of WIPO Standard ST.26. See MPEP § 2418.

Jump to MPEP Source · 37 CFR 1.833(b)(1)Sequence Listing FormatSequence Listing RequirementsSequence Listing Content
Topic

Sequence Listing Content

1 rules
StatutoryInformativeAlways
[mpep-2413-01-b-40c8625079335695050affbc]
Sequence Listing XML Must Be Valid According To DTD
Note:
The 'Sequence Listing XML' must conform to the defined Document Type Definition for all applications filed on or after July 1, 2022.

[Editor Note: This section is applicable to all applications with a filing date, or, for national phase applications, an international filing date, on or after July 1, 2022, having disclosure of one or more nucleotide and/or amino acid sequences as defined in 37 CFR 1.831(b).]

37 CFR 1.77 · 37 CFR 1.831(b)Sequence Listing ContentSequence Listing RequirementsSequence Listing Format

Citations

Primary topicCitation
Sequence Listing Content37 CFR § 1.831(b)
Sequence Listing Format37 CFR § 1.833(b)(1)
Sequence Listing FormatMPEP § 2418

Source Text from USPTO’s MPEP

This is an exact copy of the MPEP from the USPTO. It is here for your reference to see the section in context.

BlueIron Last Updated: 2025-12-31