MPEP § 2173.05(h) — Alternative Limitations (Annotated Rules)

§2173.05(h) Alternative Limitations

USPTO MPEP version: BlueIron's Update: 2025-12-31

This page consolidates and annotates all enforceable requirements under MPEP § 2173.05(h), including statutory authority, regulatory rules, examiner guidance, and practice notes. It is provided as guidance, with links to the ground truth sources. This is information only, it is not legal advice.

Alternative Limitations

This section addresses Alternative Limitations. Primary authority: 35 U.S.C. 112(b) and 35 U.S.C. 112. Contains: 2 prohibitions, 2 guidance statements, 4 permissions, and 9 other statements.

Key Rules

Topic

Alternative Limitations (MPEP 2173.05(h))

12 rules
StatutoryRecommendedAlways
[mpep-2173-05-h-496ac989670eeb7717a60357]
Alternative Limitations Acceptable for Claims
Note:
Claims defining a limitation through a list of alternatives are acceptable and should not be rejected as confusing under 35 U.S.C. 112(b) or improper.

A claim which recites a list of alternatives to define a limitation is an acceptable claim construction which should not necessarily be rejected as confusing under 35 U.S.C. 112(b) or as improper. See MPEP § 2117 for guidelines regarding the determination of whether a Markush grouping is improper.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))Disclosure Requirements
StatutoryPermittedAlways
[mpep-2173-05-h-ce872683c834133f2d9b203b]
Format of Claim Alternatives Does Not Matter
Note:
The way alternatives are formatted in claims does not affect their interpretation as long as they are clearly defined.

Treatment of claims reciting alternatives is not governed by the particular format used (e.g., alternatives may be set forth as “a material selected from the group consisting of A, B, and C” or “wherein the material is A, B, or C”). See, e.g., the Supplementary Examination Guidelines for Determining Compliance with 35 U.S.C. 112 and for Treatment of Related Issues in Patent Applications (“Supplementary Guidelines”), 76 Fed. Reg. 7162, 7166 (February 9, 2011). Claims that set forth a list of alternatives from which a selection is to be made are typically referred to as Markush claims, after the appellant in Ex parte Markush, 1925 Dec. Comm’r Pat. 126, 127 (1924). The listing of specified alternatives within a Markush claim is referred to as a Markush group or Markush grouping. Abbott Labs v. Baxter Pharmaceutical Products, Inc., 334 F.3d 1274, 1280-81, 67 USPQ2d 1191, 1196-97 (Fed. Cir. 2003) (citing to several sources that describe Markush groups).

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))Sequence Listing Format
StatutoryInformativeAlways
[mpep-2173-05-h-a03d7cf228326447e2353046]
Requirement for Markush Grouping in Claims
Note:
Claims listing alternatives from which a selection is to be made are referred to as Markush claims and must include a Markush group or grouping.

Treatment of claims reciting alternatives is not governed by the particular format used (e.g., alternatives may be set forth as “a material selected from the group consisting of A, B, and C” or “wherein the material is A, B, or C”). See, e.g., the Supplementary Examination Guidelines for Determining Compliance with 35 U.S.C. 112 and for Treatment of Related Issues in Patent Applications (“Supplementary Guidelines”), 76 Fed. Reg. 7162, 7166 (February 9, 2011). Claims that set forth a list of alternatives from which a selection is to be made are typically referred to as Markush claims, after the appellant in Ex parte Markush, 1925 Dec. Comm’r Pat. 126, 127 (1924). The listing of specified alternatives within a Markush claim is referred to as a Markush group or Markush grouping. Abbott Labs v. Baxter Pharmaceutical Products, Inc., 334 F.3d 1274, 1280-81, 67 USPQ2d 1191, 1196-97 (Fed. Cir. 2003) (citing to several sources that describe Markush groups).

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
StatutoryInformativeAlways
[mpep-2173-05-h-94c1238dd306f0274771d0b2]
Definition of Markush Claim Alternatives
Note:
This rule defines how alternatives within a Markush claim are grouped and referred to as a Markush group.

Treatment of claims reciting alternatives is not governed by the particular format used (e.g., alternatives may be set forth as “a material selected from the group consisting of A, B, and C” or “wherein the material is A, B, or C”). See, e.g., the Supplementary Examination Guidelines for Determining Compliance with 35 U.S.C. 112 and for Treatment of Related Issues in Patent Applications (“Supplementary Guidelines”), 76 Fed. Reg. 7162, 7166 (February 9, 2011). Claims that set forth a list of alternatives from which a selection is to be made are typically referred to as Markush claims, after the appellant in Ex parte Markush, 1925 Dec. Comm’r Pat. 126, 127 (1924). The listing of specified alternatives within a Markush claim is referred to as a Markush group or Markush grouping. Abbott Labs v. Baxter Pharmaceutical Products, Inc., 334 F.3d 1274, 1280-81, 67 USPQ2d 1191, 1196-97 (Fed. Cir. 2003) (citing to several sources that describe Markush groups).

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))Sequence Listing Requirements
StatutoryInformativeAlways
[mpep-2173-05-h-6ac3e7a8e1a6530e7e5ffd44]
Selection Must Be From Closed List
Note:
When using a Markush grouping, the selection must be from a closed list of alternatives (using 'consisting of'), not an open list ('comprising' or 'consisting essentially of').

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
StatutoryRecommendedAlways
[mpep-2173-05-h-c6e34e5d81468431f235dc84]
Claim Requires Closed List of Alternatives
Note:
A claim should be rejected as indefinite if it requires a material selected from an open list of alternatives in a Markush grouping.

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
StatutoryPermittedAlways
[mpep-2173-05-h-5a2fbc40acc6a07a3c63770d]
Claim Can Include Combinations of Alternatives in Markush Grouping
Note:
A claim may include qualifying language to encompass combinations or mixtures of alternatives within a Markush grouping, ensuring clarity and compliance with section 112(b) requirements.

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))Numerical Ranges and Amounts (MPEP 2173.05(c))
StatutoryPermittedAlways
[mpep-2173-05-h-c87113e638666718f2f0704b]
Breadth of Markush Claim Not Necessarily Indefinite
Note:
A claim using a large Markush grouping is not necessarily indefinite under 35 U.S.C. 112(b) despite encompassing many alternatives, unless the breadth makes it impossible to determine the metes and bounds.

A Markush grouping may include a large number of alternatives, and as a result a Markush claim may encompass a large number of alternative members or embodiments, but a claim is not necessarily indefinite under 35 U.S.C. 112(b) for such breadth. In re Gardner, 427 F.2d 786, 788, 166 USPQ 138, 140 (CCPA 1970) (“Breadth is not indefiniteness.”). In certain circumstances, however, a Markush group may be so expansive that persons skilled in the art cannot determine the metes and bounds of the claimed invention. For example, if a claim defines a chemical compound using one or more Markush groups, and that claim encompasses a massive number of distinct alternative members, the claim may be indefinite under 35 U.S.C. 112(b) if one skilled in the art cannot determine its metes and bounds due to an inability to envision all of the compounds defined by the Markush group(s). In such a circumstance, a rejection of the claim for indefiniteness under 35 U.S.C. 112(b) is appropriate.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Breadth Is Not Indefiniteness (MPEP 2173.04)35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
StatutoryProhibitedAlways
[mpep-2173-05-h-4056f5239dfb63b767931a8f]
Markush Group May Be Too Broad to Determine Metes and Bounds
Note:
A Markush group in a claim may be so expansive that it cannot be clearly defined, making the invention's scope unclear.

A Markush grouping may include a large number of alternatives, and as a result a Markush claim may encompass a large number of alternative members or embodiments, but a claim is not necessarily indefinite under 35 U.S.C. 112(b) for such breadth. In re Gardner, 427 F.2d 786, 788, 166 USPQ 138, 140 (CCPA 1970) (“Breadth is not indefiniteness.”). In certain circumstances, however, a Markush group may be so expansive that persons skilled in the art cannot determine the metes and bounds of the claimed invention. For example, if a claim defines a chemical compound using one or more Markush groups, and that claim encompasses a massive number of distinct alternative members, the claim may be indefinite under 35 U.S.C. 112(b) if one skilled in the art cannot determine its metes and bounds due to an inability to envision all of the compounds defined by the Markush group(s). In such a circumstance, a rejection of the claim for indefiniteness under 35 U.S.C. 112(b) is appropriate.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
StatutoryProhibitedAlways
[mpep-2173-05-h-1ffd2e35a003b040d264221f]
Claim with Markush Groups May Be Indefinite if Too Broad
Note:
A claim defining a chemical compound using Markush groups may be indefinite under 35 U.S.C. 112(b) if it encompasses too many distinct alternatives, making the metes and bounds unclear.

A Markush grouping may include a large number of alternatives, and as a result a Markush claim may encompass a large number of alternative members or embodiments, but a claim is not necessarily indefinite under 35 U.S.C. 112(b) for such breadth. In re Gardner, 427 F.2d 786, 788, 166 USPQ 138, 140 (CCPA 1970) (“Breadth is not indefiniteness.”). In certain circumstances, however, a Markush group may be so expansive that persons skilled in the art cannot determine the metes and bounds of the claimed invention. For example, if a claim defines a chemical compound using one or more Markush groups, and that claim encompasses a massive number of distinct alternative members, the claim may be indefinite under 35 U.S.C. 112(b) if one skilled in the art cannot determine its metes and bounds due to an inability to envision all of the compounds defined by the Markush group(s). In such a circumstance, a rejection of the claim for indefiniteness under 35 U.S.C. 112(b) is appropriate.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))Chemical Formula (MPEP 2173.05(t))
StatutoryInformativeAlways
[mpep-2173-05-h-ca15c6f9e517dd4741c0e0b3]
Optionally Language Clarification for Alternative Limitations
Note:
The rule explains how to analyze the use of 'optionally' in claim language to determine if it introduces ambiguity, requiring a rejection under 35 U.S.C. 112(b) if confusion arises.

Another alternative format which requires some analysis before concluding whether or not the language is indefinite involves the use of the term “optionally.” In Ex parte Cordova, 10 USPQ2d 1949 (Bd. Pat. App. & Inter. 1989) the language “containing A, B, and optionally C” was considered acceptable alternative language because there was no ambiguity as to which alternatives are covered by the claim. A similar holding was reached with regard to the term “optionally” in Ex parte Wu, 10 USPQ2d 2031 (Bd. Pat. App. & Inter. 1989). In the instance where the list of potential alternatives can vary and ambiguity arises, then it is proper to make a rejection under 35 U.S.C. 112(b) and explain why there is confusion.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))Use Claims (MPEP 2173.05(q))
StatutoryInformativeAlways
[mpep-2173-05-h-92181a5d427fd91c42561c45]
Optionally Included Components Must Be Clear
Note:
When a claim includes optional components (e.g., 'containing A, B, and optionally C'), the language must clearly indicate which alternatives are covered to avoid ambiguity.

Another alternative format which requires some analysis before concluding whether or not the language is indefinite involves the use of the term “optionally.” In Ex parte Cordova, 10 USPQ2d 1949 (Bd. Pat. App. & Inter. 1989) the language “containing A, B, and optionally C” was considered acceptable alternative language because there was no ambiguity as to which alternatives are covered by the claim. A similar holding was reached with regard to the term “optionally” in Ex parte Wu, 10 USPQ2d 2031 (Bd. Pat. App. & Inter. 1989). In the instance where the list of potential alternatives can vary and ambiguity arises, then it is proper to make a rejection under 35 U.S.C. 112(b) and explain why there is confusion.

Jump to MPEP SourceAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
Topic

Lack of Antecedent Basis (MPEP 2173.05(e))

5 rules
StatutoryInformativeAlways
[mpep-2173-05-h-83b72bda33ca41e724c2080c]
Alternative Limitations Not Governed by Format
Note:
Claims reciting alternatives are not required to be formatted in a specific way.

Treatment of claims reciting alternatives is not governed by the particular format used (e.g., alternatives may be set forth as “a material selected from the group consisting of A, B, and C” or “wherein the material is A, B, or C”). See, e.g., the Supplementary Examination Guidelines for Determining Compliance with 35 U.S.C. 112 and for Treatment of Related Issues in Patent Applications (“Supplementary Guidelines”), 76 Fed. Reg. 7162, 7166 (February 9, 2011). Claims that set forth a list of alternatives from which a selection is to be made are typically referred to as Markush claims, after the appellant in Ex parte Markush, 1925 Dec. Comm’r Pat. 126, 127 (1924). The listing of specified alternatives within a Markush claim is referred to as a Markush group or Markush grouping. Abbott Labs v. Baxter Pharmaceutical Products, Inc., 334 F.3d 1274, 1280-81, 67 USPQ2d 1191, 1196-97 (Fed. Cir. 2003) (citing to several sources that describe Markush groups).

Jump to MPEP SourceLack of Antecedent Basis (MPEP 2173.05(e))Disclosure RequirementsAlternative Limitations (MPEP 2173.05(h))
StatutoryInformativeAlways
[mpep-2173-05-h-5c64821b13bd056d8edd128b]
Improper Markush Language Is Indefinite
Note:
Claims using an open-ended 'comprising' in a Markush grouping are indefinite unless qualifying language is used to specify combinations or mixtures.

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP SourceLack of Antecedent Basis (MPEP 2173.05(e))35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)Board Decision Types
StatutoryInformativeAlways
[mpep-2173-05-h-785b92d28d058cbf18eddc3c]
Claim for Indefiniteness When Markush Group Is Too Broad
Note:
A claim using a Markush group is indefinite under 35 U.S.C. 112(b) if the group encompasses too many alternatives, making it impossible to determine the metes and bounds of the invention.

A Markush grouping may include a large number of alternatives, and as a result a Markush claim may encompass a large number of alternative members or embodiments, but a claim is not necessarily indefinite under 35 U.S.C. 112(b) for such breadth. In re Gardner, 427 F.2d 786, 788, 166 USPQ 138, 140 (CCPA 1970) (“Breadth is not indefiniteness.”). In certain circumstances, however, a Markush group may be so expansive that persons skilled in the art cannot determine the metes and bounds of the claimed invention. For example, if a claim defines a chemical compound using one or more Markush groups, and that claim encompasses a massive number of distinct alternative members, the claim may be indefinite under 35 U.S.C. 112(b) if one skilled in the art cannot determine its metes and bounds due to an inability to envision all of the compounds defined by the Markush group(s). In such a circumstance, a rejection of the claim for indefiniteness under 35 U.S.C. 112(b) is appropriate.

Jump to MPEP SourceLack of Antecedent Basis (MPEP 2173.05(e))Disclosure Requirements35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
StatutoryInformativeAlways
[mpep-2173-05-h-319f69df4e2eb554a5a64c3e]
Optional Alternatives Must Be Clear
Note:
Claims using optional alternatives must be clear and unambiguous to avoid rejection under 35 U.S.C. 112(b).

Another alternative format which requires some analysis before concluding whether or not the language is indefinite involves the use of the term “optionally.” In Ex parte Cordova, 10 USPQ2d 1949 (Bd. Pat. App. & Inter. 1989) the language “containing A, B, and optionally C” was considered acceptable alternative language because there was no ambiguity as to which alternatives are covered by the claim. A similar holding was reached with regard to the term “optionally” in Ex parte Wu, 10 USPQ2d 2031 (Bd. Pat. App. & Inter. 1989). In the instance where the list of potential alternatives can vary and ambiguity arises, then it is proper to make a rejection under 35 U.S.C. 112(b) and explain why there is confusion.

Jump to MPEP SourceLack of Antecedent Basis (MPEP 2173.05(e))35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)Alternative Limitations (MPEP 2173.05(h))
StatutoryPermittedAlways
[mpep-2173-05-h-69e76c494e0ec644e466fd8e]
Optionally Clause Can Cause Indefiniteness
Note:
When the list of potential alternatives varies and causes ambiguity, a rejection under 35 U.S.C. 112(b) is proper to explain the confusion.

Another alternative format which requires some analysis before concluding whether or not the language is indefinite involves the use of the term “optionally.” In Ex parte Cordova, 10 USPQ2d 1949 (Bd. Pat. App. & Inter. 1989) the language “containing A, B, and optionally C” was considered acceptable alternative language because there was no ambiguity as to which alternatives are covered by the claim. A similar holding was reached with regard to the term “optionally” in Ex parte Wu, 10 USPQ2d 2031 (Bd. Pat. App. & Inter. 1989). In the instance where the list of potential alternatives can vary and ambiguity arises, then it is proper to make a rejection under 35 U.S.C. 112(b) and explain why there is confusion.

Jump to MPEP SourceLack of Antecedent Basis (MPEP 2173.05(e))Disclosure Requirements35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
Topic

35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)

3 rules
StatutoryInformativeAlways
[mpep-2173-05-h-d1f3bfe5777f1dcd6b69c8fd]
Claim Must Use Closed Markush Grouping
Note:
A claim must use a closed Markush grouping to clearly define the alternatives, avoiding indefinite language like 'comprising' or 'consisting essentially of'.

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP Source35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)Board Decision TypesAlternative Limitations (MPEP 2173.05(h))
StatutoryInformativeAlways
[mpep-2173-05-h-0ec8c253894b21a0928d3b6f]
Claim Must Use Closed Markush Groupings
Note:
A claim must use a closed group of alternatives, not an open list, to avoid indefiniteness under 35 U.S.C. 112(b).

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP Source35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)Board Decision TypesAlternative Limitations (MPEP 2173.05(h))
StatutoryInformativeAlways
[mpep-2173-05-h-256f0c6c561a91d625019171]
Claim Must Use Closed Markush Grouping
Note:
Claims must use a closed Markush grouping to clearly define the alternatives, avoiding indefinite language.

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP Source35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)Board Decision TypesAlternative Limitations (MPEP 2173.05(h))
Topic

Board Decision Types

1 rules
StatutoryInformativeAlways
[mpep-2173-05-h-a72c54d1d2d7fc6c2a6c4c15]
Pending Claims Require Specific Language
Note:
The pending claims must use specific language to avoid being indefinite under § 112(b) due to improper Markush groupings.

A Markush grouping is a closed group of alternatives, i.e., the selection is made from a group “consisting of” (rather than “comprising” or “including”) the alternative members. Abbott Labs., 334 F.3d at 1280, 67 USPQ2d at 1196. If a Markush grouping requires a material selected from an open list of alternatives (e.g., selected from the group “comprising” or “consisting essentially of” the recited alternatives), the claim should generally be rejected under 35 U.S.C. 112(b) as indefinite because it is unclear what other alternatives are intended to be encompassed by the claim. See In re Kiely, 2022 USPQ2d 532 at 2* (Fed. Cir. 2022) (each independent claim recites "a selection from the group comprising a person, an animal, an animated character, a creature, an alien, a toy, a structure, a vegetable, and a fruit.” … (emphasis added). “Given the breadth of variation among the specified alternatives and the use of the open-ended word ’comprising’ to define the scope of the list, we affirm the Board's conclusion that the pending claims recite improper Markush language and are indefinite under § 112(b).”). If a claim is intended to encompass combinations or mixtures of the alternatives set forth in the Markush grouping, the claim may include qualifying language preceding the recited alternatives (such as “at least one member” selected from the group), or within the list of alternatives (such as “or mixtures thereof”). Id. at 1281. See also MPEP § 2111.03.

Jump to MPEP SourceBoard Decision TypesAlternative Limitations (MPEP 2173.05(h))Lack of Antecedent Basis (MPEP 2173.05(e))

Citations

Primary topicCitation
Alternative Limitations (MPEP 2173.05(h))
Lack of Antecedent Basis (MPEP 2173.05(e))
35 U.S.C. § 112
35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
Alternative Limitations (MPEP 2173.05(h))
Board Decision Types
Lack of Antecedent Basis (MPEP 2173.05(e))
35 U.S.C. § 112(b)
35 U.S.C. 112(b) – Definiteness (MPEP 2171-2173)
Alternative Limitations (MPEP 2173.05(h))
Board Decision Types
Lack of Antecedent Basis (MPEP 2173.05(e))
MPEP § 2111.03
Alternative Limitations (MPEP 2173.05(h))MPEP § 2117
MPEP § 803.02
Alternative Limitations (MPEP 2173.05(h))
Lack of Antecedent Basis (MPEP 2173.05(e))
In re Gardner, 427 F.2d 786, 788, 166 USPQ 138, 140 (CCPA 1970)

Source Text from USPTO’s MPEP

This is an exact copy of the MPEP from the USPTO. It is here for your reference to see the section in context.

BlueIron Last Updated: 2025-12-31