How does the USPTO process Sequence Listing XML files?

This page is an FAQ based on guidance from the Manual of Patent Examining Procedure. It is provided as guidance, with links to the ground truth sources. This is information only: it is not legal advice.

The USPTO uses the Sequence Listing Information Control (SLIC) system to process “Sequence Listing XML” files. As stated in MPEP 2419: “At the USPTO, the Sequence Listing Information Control (SLIC) system will be responsible for processing of a ‘Sequence Listing XML’ and exporting the sequence data for publication and grant.” This system ensures that the sequence data is properly handled and prepared for publication in patent documents.