How should the Sequence Listing XML be submitted in a patent application?

MPEP 2415 states that the Sequence Listing XML should be submitted “as a separate part of the specification.” This means it should be a distinct section within the patent application, separate from other parts of the disclosure. The Sequence Listing XML must conform to the requirements set forth in 37 CFR 1.831(a), which defines the specific format and content requirements for this submission.

XML Format Required for Sequence Listings MPEP 2415 Informative
Sequence Listing XML Required for Filing MPEP 2415 Required
Sequence Listing XML Required for Filing Date On or After July 1, 2022 MPEP 2415 Required
International Filing Date for National Phase Applications MPEP 2415 Informative