What is the required encoding for a “Sequence Listing XML” file?

This page is an FAQ based on guidance from the Manual of Patent Examining Procedure. It is provided as guidance, with links to the ground truth sources. This is information only: it is not legal advice.

The “Sequence Listing XML” file must be encoded using Unicode UTF-8. As stated in MPEP 2413.01(a):

“The ‘Sequence Listing XML’ as required by § 1.831(a) must be presented as a single file in XML 1.0 encoded using Unicode UTF–8, where the character set complies with paragraphs 40 and 41 and Annex IV of WIPO Standard ST.26 (incorporated by reference, see § 1.839).”

This encoding requirement ensures compatibility and proper handling of the sequence listing data across different systems and platforms.