How should amino acid sequence variants produced by alternative splicing be represented?

According to the table in MPEP 2412.05(c), amino acid sequence variants produced by alternative splicing should be represented as follows:

  • Feature Key: VAR_SEQ
  • Qualifier: note
  • Use: For variants produced by alternative splicing, alternative promoter usage, alternative initiation, and ribosomal frameshifting

This representation allows for accurate documentation of protein variants resulting from different cellular processes, which is essential for biotechnology patent applications involving protein sequences.

To learn more:

Topics: MPEP 2400 - Biotechnology, MPEP 2412.05(C) - Representation And Inclusion Of Variants, Patent Law, Patent Procedure
Tags: Alternative Splicing, amino acid sequences, biotechnology patents, Protein Variants, sequence listing