What is the correct format for presenting amino acid symbols in a Sequence Listing?

According to MPEP 2423.01, the correct format for presenting amino acid symbols in a Sequence Listing is as follows:

  • Three-letter symbols for amino acids are required in the Sequence Listing.
  • The three-letter symbols must be presented using uppercase for the first character and lowercase for the remaining two characters.

The MPEP states: “In 37 CFR 1.822(b) and 37 CFR 1.822(d), the use of three-letter symbols for amino acids is required in the ‘Sequence Listing’. The three-letter symbols must be presented using the upper case for the first character and lower case for the remaining two characters.”

Additionally, the MPEP encourages the use of three-letter symbols throughout the entire disclosure for easier readability: “Applicants are encouraged to use the three-letter symbols for amino acids throughout the disclosure, instead of the one-letter symbols, for easier reading of the application and any patent issuing therefrom.”

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Topics: MPEP 2400 - Biotechnology, MPEP 2423.01 - Format And Symbols To Be Used In A "Sequence Listing", Patent Law, Patent Procedure
Tags: Amino Acid Symbols, biotechnology patents, patent application format, sequence listing, Three-Letter Symbols