What are the format requirements for sequence listings in patent applications?

This page is an FAQ based on guidance from the Manual of Patent Examining Procedure. It is provided as guidance, with links to the ground truth sources. This is information only: it is not legal advice.

The format requirements for sequence listings in patent applications are specified in MPEP 2421.02 and 37 CFR 1.821-1.825. Key format requirements include:

• Sequence listings must be in a separate part of the disclosure.
• They should be presented in the standard sequence listing format.
• The listing must be readable by both humans and computers.
• It must contain numeric identifiers to organize the data elements of the sequence listing.

The MPEP states: “The sequence listing must be presented in the manner specified in § 1.821 through § 1.825.” This standardized format ensures consistency and facilitates efficient processing and searching of sequence information.