When did the new rules for “modified amino acids” in patent applications come into effect?

This page is an FAQ based on guidance from the Manual of Patent Examining Procedure. It is provided as guidance, with links to the ground truth sources. This is information only: it is not legal advice.

The new rules regarding “modified amino acids” in patent applications came into effect on July 1, 2022. This is clearly stated in the MPEP 2412.03(c):

[Editor Note: This section is applicable to all applications filed on or after July 1, 2022, having disclosures of nucleotide and/or amino acid sequences as defined in 37 CFR 1.831(b).]

This means that any patent application filed on or after this date must adhere to these new rules when disclosing nucleotide and/or amino acid sequences, including modified amino acids.