What character encoding is required for the “Sequence Listing XML” file?

This page is an FAQ based on guidance from the Manual of Patent Examining Procedure. It is provided as guidance, with links to the ground truth sources. This is information only: it is not legal advice.

The “Sequence Listing XML” file must use Unicode UTF-8 character encoding. According to MPEP 2413.02:

“In order for the USPTO to be able to process the .xml file containing the “Sequence Listing XML”, all characters must be encoded using Unicode UTF-8.“

This requirement ensures that the file can be properly read and processed by USPTO systems. Unicode UTF-8 encoding supports a wide range of characters and is the standard for XML files in many applications, including patent submissions.