How should unknown amino acids be represented in a sequence listing?

The MPEP 2412.05(d) provides guidance on representing unknown amino acids in sequence listings: Use the symbol ‘X’ to represent unknown amino acids Provide further description in a feature table Use the feature key “UNSURE” and optionally the qualifier “note” The MPEP states, “Any “unknown” amino acid must be represented by the symbol “X” in the…

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What are examples of universal facts that can be shown by non-prior art references?

Non-prior art references can be used to show universal facts in patent examination. The MPEP 2124 provides several examples of such universal facts: Characteristics and properties of a material Scientific truisms Whether undue experimentation would have been required at the filing date Whether a parameter was critical or not The accuracy of statements in the…

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What is the “unity of design” requirement in international design applications?

The “unity of design” requirement in international design applications refers to the principle that an application should contain only one independent and distinct design. According to MPEP 2920.05(b): “The examiner should determine whether the application complies with the unity of design requirement. This requirement is considered during both formalities review and substantive examination.” If an…

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How is unity of invention assessed for nucleotide sequences in international patent applications?

For international patent applications filed under the Patent Cooperation Treaty (PCT) and national stage applications filed under 35 U.S.C. 371, the assessment of unity of invention for nucleotide sequences follows specific guidelines. MPEP 2434 directs examiners to: “See MPEP ยง 1850 for treatment of claims containing nucleotide sequences that lack unity of invention in international…

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What constitutes “unintentional delay” in paying maintenance fees?

“Unintentional delay” in paying maintenance fees is a crucial concept for reinstating expired patents. According to MPEP 2590: “A person seeking reinstatement of an expired patent should not make a statement that the delay in payment of the maintenance fee was unintentional unless the entire delay was unintentional, including the period from discovery that the…

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