What are the standard single-letter codes for modified and unusual nucleotides in WIPO ST.25? WIPO ST.25 provides standard single-letter codes for modified and unusual nucleotides in sequence listings. According to MPEP 2423: “The nucleotides listed in Appendix 2, Table 2, are the only permitted nucleotides. Where a sequence includes “other” nucleotides, they must be represented…

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