What is a Sequence Identifier (SEQ ID NO) and how is it used in patent applications?

A Sequence Identifier (SEQ ID NO) is a unique number assigned to each disclosed nucleic acid and/or amino acid sequence in a patent application. According to MPEP 2422.01:

37 CFR 1.821(d) and 37 CFR 1.823(a)(5) require that each disclosed nucleic acid and/or amino acid sequence in the application appear separately in the “Sequence Listing”, with each sequence further being assigned a sequence identifier, referred to as “SEQ ID NO:” or the like.

Key points about Sequence Identifiers:

  • They must begin with 1 and increase sequentially by integers.
  • Each sequence must have a different number for identification.
  • Sequences should be presented in numerical order in the “Sequence Listing” where practical.
  • When discussing a sequence in the description or claims, a reference to its SEQ ID NO is required at all occurrences.
  • SEQ ID NOs can be used to discuss or claim parts of a sequence (e.g., “residues 14 to 243 of SEQ ID NO:23”).

The use of SEQ ID NOs provides a shorthand way for applicants to discuss and claim their inventions without restricting how an invention can be claimed.

To learn more:

Topics: MPEP 2400 - Biotechnology, MPEP 2422.01 - Nucleotide And/Or Amino Acids Disclosures Requiring A "Sequence Listing", Patent Law, Patent Procedure
Tags: amino acid sequences, nucleotide sequences, patent applications, Seq Id No, Sequence Identifier, sequence listing