What symbols should be used to represent amino acid sequences?
According to WIPO Standard ST.26, amino acids in a sequence must be represented using the one-letter codes specified in Table 3: List of Amino Acids Symbols. Key points include: Only uppercase letters must be used. Each symbol represents only one residue. Use the most restrictive symbol for ambiguities (e.g., “B” for Asp or Asn, not…
Read MoreHow are amino acids with ambiguous positions represented in sequence listings?
How are amino acids with ambiguous positions represented in sequence listings? The MPEP 2412.05 provides guidance on representing amino acids with ambiguous positions: “Where an amino acid can be one of two or more alternatives at a given position in a sequence, the preferred amino acids should be shown in the sequence and the alternatives…
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