What is considered a “specifically defined” nucleotide or amino acid?
According to MPEP 2412.03(a), “specifically defined” refers to: For nucleotides: any nucleotide other than those represented by the symbol “n” For amino acids: any amino acid other than those represented by the symbol “X” The MPEP cites WIPO Standard ST.26, which provides tables of symbols for nucleotides and amino acids. For example, ‘a’ represents adenine,…
Read MoreWhat sequences must be included in a “Sequence Listing XML”?
According to MPEP 2412.03, the following sequences must be included in a “Sequence Listing XML”: Unbranched sequences or linear regions of branched sequences containing 4 or more specifically defined amino acids forming a single peptide backbone Unbranched sequences or linear regions of branched sequences of 10 or more specifically defined nucleotides joined by phosphodiester linkages…
Read MoreWhat sequences are excluded from a Sequence Listing XML?
According to MPEP 2412.03, certain sequences must be excluded from a Sequence Listing XML: Sequences having fewer than 10 specifically defined nucleotides Sequences having fewer than 4 specifically defined amino acids The MPEP cites 37 CFR 1.831(j), which states: A “Sequence listing XML” must not include any sequences having fewer than 10 specifically defined nucleotides,…
Read MoreWhat is considered a “nucleotide” in a Sequence Listing XML?
According to MPEP 2412.03(d), a “nucleotide” in a Sequence Listing XML includes: Any nucleotide Nucleotide analogs Modified nucleotides The MPEP, citing WIPO Standard ST.26, specifies that a nucleotide must contain: A backbone moiety (e.g., 2′ deoxyribose 5′ monophosphate or an analogue) Either a nucleobase (including modified or synthetic purines or pyrimidines) or an “AP site”…
Read MoreWhat is considered an “amino acid” in a Sequence Listing XML?
According to MPEP 2412.03(b), an “amino acid” in a Sequence Listing XML includes: Any D- or L-amino acid Modified amino acids as defined in WIPO Standard ST.26 Amino acids with modified or synthetic side chains The MPEP states: Amino acids will be construed as unmodified L-amino acids unless further described in a feature table. It’s…
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