When did the requirements for Sequence Listing XML format come into effect?

This page is an FAQ based on guidance from the Manual of Patent Examining Procedure. It is provided as guidance, with links to the ground truth sources. This is information only: it is not legal advice.

The requirements for the Sequence Listing XML format came into effect for certain patent applications filed on or after July 1, 2022. According to the editor’s note in MPEP 2412.05(a):

“[Editor Note: This section is applicable to all applications filed on or after July 1, 2022, having disclosures of nucleotide and/or amino acid sequences as defined in 37 CFR 1.831(b).”

This change reflects the transition to the new WIPO Standard ST.26 for sequence listings, which replaced the previous Standard ST.25. The new format aims to improve the quality and consistency of sequence data in patent applications globally.

Applicants filing patent applications with nucleotide and/or amino acid sequence disclosures on or after this date must comply with these new XML-based requirements for their sequence listings.