What is the status of peptide nucleic acid (PNA) residues in amino acid sequence listings?

According to MPEP 2412.03(b), peptide nucleic acid (PNA) residues have a special status in amino acid sequence listings. The MPEP clearly states:

“A peptide nucleic acid (PNA) residue is not considered an amino acid, but is considered a nucleotide.”

This distinction is important for patent applicants and examiners because:

  • PNA residues should not be included in amino acid sequence listings.
  • PNA residues should instead be treated as nucleotides and included in nucleotide sequence listings.
  • This classification affects how PNA-containing molecules are represented and searched in patent databases.

To learn more:

Topics: MPEP 2400 - Biotechnology, MPEP 2412.03(B) - "Amino Acid", Patent Law, Patent Procedure
Tags: Biotechnology, Peptide Nucleic Acid, Pna, sequence listing