How does WIPO Standard ST.26 define “unknown” or “other” nucleotides and amino acids?

MPEP 2412.03(a) refers to WIPO Standard ST.26, which defines “unknown” or “other” nucleotides and amino acids using specific symbols:

  • For nucleotides, the symbol “n” represents “unknown” or “other”
  • For amino acids, the symbol “X” represents “unknown” or “other”

The MPEP provides tables for both nucleotide and amino acid symbols, stating:

n a or c or g or t/u; “unknown” or “other”

X A or R or N or D or C or Q or E or G or H or I or L or K or M or F or P or O or S or U or T or W or Y or V; “unknown” or “other”

These symbols are not considered “specifically defined” and are used when the exact nucleotide or amino acid is unknown or not listed in the standard set.

To learn more:

Topics: MPEP 2400 - Biotechnology, MPEP 2412.03(A) - "Specifically Defined", Patent Law, Patent Procedure
Tags: Sequence Symbols, Unknown Amino Acids, Unknown Nucleotides, wipo standard st.26