How can I submit a replacement “Sequence Listing XML” file to the USPTO?

There are two methods for submitting a replacement “Sequence Listing XML” file to the USPTO:

  1. Via the USPTO patent electronic filing system (Patent Center)
  2. On a read-only optical disc, if the file size exceeds the upload limit of Patent Center

According to MPEP 2414.03: A compliant replacement “Sequence Listing XML” submitted as an XML file containing the entire “Sequence Listing XML,” including any additions, deletions, or replacements of sequence information, using either the USPTO Patent Electronic Filing System (currently, XML files can only be submitted via Patent Center) or a read-only optical disc that is mailed into the Office if the size of “Sequence Listing XML” file exceeds the upload limit of Patent Center

If submitting via optical disc, it must be labeled as “REPLACEMENT MM/DD/YYYY” with the creation date indicated.

To learn more:

Topics: Deleting From, MPEP 2400 - Biotechnology, MPEP 2414.03 - Amendment Adding To, Or Replacing Sequence Information In A "Sequence Listing Xml" Under 37 Cfr 1.835(B), Patent Law, Patent Procedure
Tags: electronic filing, Optical Disc, sequence listing xml, USPTO