What is considered a “modified amino acid” according to the MPEP?

According to MPEP 2412.03(c), a “modified amino acid” is defined as follows:

“Modified amino acid” includes any amino acid as described in paragraph 3(e) of WIPO Standard ST.26.

This definition is further elaborated in WIPO Standard ST.26, which states that a modified amino acid is any amino acid other than the 22 standard amino acids (20 common amino acids plus pyrrolysine and selenocysteine). This includes naturally occurring modified amino acids as well as synthetic modifications.

To learn more:

• modified amino acid
• WIPO Standard ST.26
• patent application
• sequence disclosure